![]() ![]() With promising results, both for the delay of cognitive symptoms and the reduction of brain amyloid burden. ![]() ĭifferentiating cases of early dementia from MCI is essential, as there are currently studies involving interventions with lecanemab antibodies in cases of cognitive impairment related to Alzheimer’s dementia. This varied data can be explained by the source of subjects as the main factor, where studies with self-selected participants found higher conversion rates to dementia. The conversion rate per year of people with MCI to Alzheimer’s disease varies greatly from 12 to 31% depending on the study. MCI is characterized by the presence of cognitive complaints and cognitive impairment (memory and/or other domains), and preserved functional abilities. Mild cognitive impairment (MCI), also called mild neurocognitive disorder according to DSM 5, is a transitional state between normal aging and dementia. Future studies should focus on validating the audiovisual MoCA using other target population groups in order to expand the use of this remote screening test. The test demonstrated a great ability to discriminate older adults with MCI from cognitively healthy adults. The translated audiovisual MoCA is a valid and reliable cognitive screening test that can be administered remotely in older adults in Brazil. The audiovisual MoCA was represented as a unifactorial adjusted model, the composite reliability value was acceptable and a cutoff point of ≥23 reached adequate sensitivity and specificity at 0.77 and 0.92, respectively. The psychometric properties of the audiovisual MoCA showed good convergent validity. Statistical analyses were performed in order to assess the validity of the test and the cutoff score. Participants were classified into two groups: cognitively healthy or mild cognitive impairment (MCI). One hundred and fourteen older adults were recruited from the community and demographic, functional, mood, and cognitive data were collected. This study aimed to translate and validate the audiovisual Montreal Cognitive Assessment (MoCA)for older adults in Brazil. All rights reserved.The use of a reliable remote cognitive screening test for older adults is crucial for the diagnosis of cognitive impairment. The MoCA test is a valid and reliable tool for screening for CI in patients with multiple sclerosis.Ĭognitive impairment Deterioro cognitivo Esclerosis múltiple Montreal Cognitive Assessment Multiple sclerosis Scale validation Validación de escala.Ĭopyright © 2019 Sociedad Española de Neurología. The optimal cut-off point on the ROC curve was 25-26, yielding 91% sensitivity and 93% specificity. The correlation coefficient between total Brief Neuropsychological Battery and MoCA test scores was 0.82. ![]() The MoCA test showed good internal consistency (Cronbach alpha, 0.822) and interobserver and test-retest reliability (intraclass correlation coefficient 0.80 and 0.96, respectively). The prevalence of CI was 21.2% according to findings from the Brief Neuropsychological Battery, and 25% according to the MoCA test. We analysed the reliability (internal consistency, interobserver reliability, and test-retest reliability), construct validity (factor analysis, Pearson correlation coefficient, and coefficient of determination), and criterion validity (ROC curve, sensitivity, specificity, total agreement, positive and negative predictive values, positive and negative likelihood ratios, and Fagan nomogram) of the MoCA test in this population. We recruited 52 patients with multiple sclerosis (61.5% women mean age : 41.7 years). We aimed to evaluate the diagnostic validity and reliability of the Montreal Cognitive Assessment (MoCA) test as a screening tool for CI in patients with multiple sclerosis, as compared against the Brief Neuropsychological Battery. Simpler tests are needed to detect cognitive impairment in daily clinical practice. The neuropsychological batteries traditionally used for the assessment of cognitive impairment (CI) in patients with multiple sclerosis are complex tests requiring a long time to administer.
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